Principles of preoperative chemotherapy

Oesophageal cancer: preoperative chemotherapy.

The optimal management of localised oesophageal cancer remains controversial. Indeed, currently utilised strategies are clearly unsatisfactory, given that most randomised trials report overall 5-year survivals of 20% or less for patients undergoing surgical resection. The rationale behind preoperative chemotherapy is two-fold: (i) to downstage or downsize the primary tumour in order to ensure c...

Principles of Cancer Chemotherapy

Principles of chemotherapy.

Original Publication: Elisabeth Åvall Lundqvist, Keiichi Fujiwara and Muhieddine Seoud, Principles of chemotherapy, 2015, International Journal of Gynecology & Obstetrics, (131), S146-S149. http://dx.doi.org/10.1016/j.ijgo.2015.06.011 Copyright: 2015 Published by Elsevier Ireland Ltd. on behalf of International Federation of Gynecology and Obstetrics. This is an open access article under the CC...

The principles of chemotherapy.

This introduction to the collected articles on chemotherapy which have appeared recently in the POSTGRADUATE MEDICAL JOURNAL, is intended to deal only with general aspects of the subject. Some of the principles will doubtless appear very obvious, but there is perhaps no harm in repetition concerning such an important branch of medical science. No references to the literature are given here as t...

Bevacizumab with preoperative chemotherapy versus preoperative chemotherapy alone for colorectal cancer liver metastases

This study aimed to assess the efficacy and safety of bevacizumab plus preoperative chemotherapy as first-line treatment for liver-only metastatic colorectal cancer in Chinese patients compared with those of preoperative chemotherapy alone.Patients with histologically confirmed liver-only metastatic colorectal cancer were sequentially reviewed, and received either preoperative chemotherapy plus...